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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRMT3 All Species: 29.39
Human Site: S343 Identified Species: 53.89
UniProt: O60678 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60678 NP_005779.1 531 59903 S343 L F E S M L D S V L Y A K N K
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001092890 531 59784 S343 I L Q N I I T S M A E T K N Y
Dog Lupus familis XP_534089 541 60618 S353 L F E S M L D S V L Y A K N K
Cat Felis silvestris
Mouse Mus musculus Q922H1 532 59884 S340 L F E S M L D S V L Y A K S K
Rat Rattus norvegicus O70467 528 59401 S340 L F E S M L D S V L Y A K S K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505718 571 63850 S383 L F E S M L D S V I Y A K S K
Chicken Gallus gallus XP_420907 526 59430 S338 L F E S M L D S V I Y A K D K
Frog Xenopus laevis Q8AV13 369 42306 G187 D K W L T P D G L I F P D R A
Zebra Danio Brachydanio rerio Q5RGQ2 419 48204 G237 D K W L K P G G F M F P D R A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396035 525 60169 T339 L F E G M L D T V I Y A R D N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001192186 519 58632 D331 K G R L E D L D M P V E K S I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O82210 366 41153 G184 N K W L V D G G I V L P D K A
Baker's Yeast Sacchar. cerevisiae P38074 348 39768 C166 G L I F P D K C S I H L A G L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 94.1 90.9 N.A. 89.8 89.2 N.A. 78.8 70.8 35.4 35.7 N.A. N.A. 42.5 N.A. 45
Protein Similarity: 100 N.A. 96.8 95.1 N.A. 93.9 93.9 N.A. 85.9 83.2 49.1 52.3 N.A. N.A. 62.5 N.A. 63.6
P-Site Identity: 100 N.A. 20 100 N.A. 93.3 93.3 N.A. 86.6 86.6 6.6 0 N.A. N.A. 60 N.A. 6.6
P-Site Similarity: 100 N.A. 60 100 N.A. 100 100 N.A. 100 100 26.6 13.3 N.A. N.A. 86.6 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. 33.1 31.2 N.A.
Protein Similarity: N.A. N.A. N.A. 48.2 43.3 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 8 0 54 8 0 24 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % C
% Asp: 16 0 0 0 0 24 62 8 0 0 0 0 24 16 0 % D
% Glu: 0 0 54 0 8 0 0 0 0 0 8 8 0 0 0 % E
% Phe: 0 54 0 8 0 0 0 0 8 0 16 0 0 0 0 % F
% Gly: 8 8 0 8 0 0 16 24 0 0 0 0 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % H
% Ile: 8 0 8 0 8 8 0 0 8 39 0 0 0 0 8 % I
% Lys: 8 24 0 0 8 0 8 0 0 0 0 0 62 8 47 % K
% Leu: 54 16 0 31 0 54 8 0 8 31 8 8 0 0 8 % L
% Met: 0 0 0 0 54 0 0 0 16 8 0 0 0 0 0 % M
% Asn: 8 0 0 8 0 0 0 0 0 0 0 0 0 24 8 % N
% Pro: 0 0 0 0 8 16 0 0 0 8 0 24 0 0 0 % P
% Gln: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 8 0 0 0 0 0 0 0 0 0 8 16 0 % R
% Ser: 0 0 0 47 0 0 0 54 8 0 0 0 0 31 0 % S
% Thr: 0 0 0 0 8 0 8 8 0 0 0 8 0 0 0 % T
% Val: 0 0 0 0 8 0 0 0 54 8 8 0 0 0 0 % V
% Trp: 0 0 24 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 54 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _